What is a seizure? 

Seizures are one of the most frequently seen neurological problems in cats. A seizure is also known as a convulsion or fit. It may have all or any combination of the following: 

  1. Loss or derangement of consciousness
  2. Contractions of all the muscles in the body
  3. Changes in mental awareness from non-responsiveness to hallucinations
  4. Involuntary urination, defecation, or salivation
  5. Behavioral changes, including non-recognition of owner, viciousness, pacing, and running in circles 

What are the three phases of a seizure? 

Seizures consist of three components: 

  1. The pre-ictal phase, or aura, is a period of altered behavior in which the cat may hide, appear nervous, or seek out the owner. It may be restless, nervous, shaking, or salivating. This may last a few seconds to a few hours. 
  2. The ictal phase is the seizure itself and lasts from a few seconds to about five minutes. During this period, all of the muscles of the body contract strongly. The cat usually falls on its side and seems paralyzed while shaking. The head will be drawn backward. Urination, defecation, and salivation often occur. If it is not over within five minutes, the cat is said to be in status epilepticus or a prolonged seizure. 
  3. During the post-ictal phase, there is confusion, disorientation, salivation, pacing, restlessness, and/or temporary blindness. There is no direct correlation between the severity of the seizure and the duration of the post-ictal phase. 

Is the cat in trouble during a seizure? 

Despite the dramatic signs of a seizure, the cat feels no pain, only bewilderment. Cats do not swallow their tongues. If you put your fingers into its mouth, you will do no benefit to your pet and will run a high risk of being bitten very badly. The important thing is to keep the cat from falling and hurting itself. As long as it is on the floor or ground, there is little chance of harm occurring. 

If seizures continue for longer than a few minutes, the body temperature begins to rise. If hyperthermia develops secondary to a seizure, another set of problems may have to be addressed. 

What causes seizures? 

There are many, many causes of seizures. Epilepsy is the most common and of least consequence to the cat. The other extreme includes severe diseases such as brain tumors. Fortunately, most are due to epilepsy. 

Now that the seizure is over, can anything be done to understand why it happened? 

When a seizure occurs, we begin by taking a thorough history concentrating on possible exposure to poisonous or hallucinogenic substances or history of head trauma. We also perform a physical examination, a basic battery of blood tests, and an electrocardiogram (EKG). These tests rule out disorders of the liver, kidneys, heart, electrolytes, and blood sugar level. 

If these tests are normal and there is no exposure to poison or recent trauma, further diagnostics may be performed depending on the severity and frequency of the seizures. Occasional seizures are of less concern than when the seizures are becoming more severe and frequent. In this instance, a spinal fluid tap and fluid analysis may be performed. Depending on availability, specialized imaging of the head with a CAT scan or MRI might be performed. Fortunately, these additional tests are usually not needed. 

What can be done to prevent future seizures? 

We generally prescribe 1-2 weeks of anticonvulsant therapy. If there are no more seizures during that time, the anticonvulsants are gradually discontinued. The next treatment is determined by how long it takes for another seizure to occur. That may be days, months, or years. At some point, many cats have seizures frequently enough to justify continuous anticonvulsant therapy. Since that means that medication must be given every 12 to 24 hours for the rest of the cat's life, we do not recommend that until seizures occur about every 30 days or unless they last more than five minutes. 

It is important to avoid sudden discontinuation of any anticonvulsant medication. Even normal cats may be induced to seizure if placed on anticonvulsant medication and then abruptly withdrawn from it. Your veterinarian can outline a schedule for discontinuing the medication. 

Could other drugs be tried to treat or prevent seizures? 

Some cats with seizures are known to have non-suppurative meningoencephalitis. This is a disease that causes inflammation in the brain and tissue coverings around the brain. It is not caused by infection. The only way to make a confirmed diagnosis is with an autopsy. However, it usually responds well to corticosteroids (“cortisone “ or “steroids”). Therefore, corticosteroids may be tried when phenobarbital is not effective. 

You mentioned status epilepticus. What does that mean? 

Status epilepticus bears special note. It is characterized by a seizure that lasts more than five minutes. When it occurs, the cat's life is endangered. Unless intravenous medication is given promptly, the patient may die. If this occurs, you should seek treatment by a veterinarian immediately. 

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